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What Is CRPS?

CRPS is a chronic pain condition that usually affects one limb (arm, leg, hand, or foot) after an injury, surgery, stroke, or heart attack. It’s characterised by prolonged or excessive pain that can be out of proportion to the initial trauma. CRPS can also cause swelling, changes in skin temperature or colour, and other symptoms such as altered sweating and sensitivity to touch.

There are two main types of CRPS:

  • Type I (Reflex Sympathetic Dystrophy): Occurs after an illness or injury that didn’t directly damage the nerves in the affected limb.

  • Type II (Causalgia): Involves an identifiable nerve injury.

Regardless of type, the hallmark is persistent, disproportionate pain that can lead to substantial disability and emotional distress if not addressed early.

How Does CRPS Develop?

While the exact cause of CRPS isn’t fully understood, it’s believed to involve a dysregulated response in the nervous system and immune system. After an injury or surgery, your body’s normal healing mechanisms can go awry—leading to abnormal inflammation, nerve sensitivity, and pain signals that persist long after the tissues have healed.

Risk Factors

  • Trauma or Surgery: Most commonly seen after fractures, soft-tissue injuries, or limb surgeries.

  • Immobilisation: Prolonged immobilisation (e.g., wearing a cast) can contribute to pain syndromes.

  • Genetic Predisposition: Some people may be more genetically susceptible to maladaptive inflammatory or neurological responses.

  • Smoking: Tobacco use can impair circulation and healing, potentially increasing CRPS risk.

  • Psychological Stress: While not a direct cause, high stress can worsen or perpetuate chronic pain.

Prevention Strategies

  1. Early Mobilisation:

    • Whenever possible, start gentle movement and physiotherapy soon after an injury or surgery. This helps maintain blood flow, reduce swelling, and support the nervous system’s return to baseline.

  2. Adequate Pain Control:

    • Uncontrolled acute pain can lead to chronic pain pathways developing. Work with your doctor to ensure you’re getting the right pain management, which may include medications such as anti-inflammatories or short-term opioids (used judiciously), nerve pain medications, or local nerve blocks.

  3. Vitamin C Supplementation:

    • Some studies suggest that taking Vitamin C after certain fractures (especially wrist fractures) may lower the likelihood of CRPS development. While results vary, it’s a low-risk intervention to discuss with your healthcare provider.

  4. Optimise Overall Health:

    • Good nutrition, adequate hydration, and maintaining a healthy lifestyle (avoiding smoking, minimising alcohol) all support better healing and can reduce the risk of chronic pain syndromes.

  5. Stress Management:

    • Chronic stress can exacerbate inflammation and pain. Techniques like mindfulness, relaxation exercises, and proper sleep can be protective.

Signs and Symptoms to Watch For

  • Prolonged Pain: Pain that lasts longer than typical post-injury healing time.

  • Swelling and Stiffness: Particularly if it persists or worsens over time.

  • Temperature or Colour Changes: One limb appears warmer or cooler, redder or paler.

  • Excessive Sweating: Hyperhidrosis can sometimes occur in the affected region.

  • Muscle Spasms or Tremors: The affected limb may display involuntary movements.

If you notice these symptoms, seek medical advice early. Timely recognition is key to preventing long-term complications.

Management Approaches

  1. Pain Medications and Therapies:

    • Medications: Anti-inflammatories (e.g., NSAIDs), nerve pain agents (e.g., gabapentin, pregabalin), or topical treatments (capsaicin, lidocaine).

    • Nerve Blocks: Injecting anaesthetic agents around the affected nerves to disrupt abnormal pain signals.

  2. Physiotherapy:

    • Gentle, guided exercises to improve range of motion and reduce stiffness. A physiotherapist experienced in chronic pain can tailor exercises to ensure gradual, non-aggravating progress.

  3. Occupational Therapy:

    • Focuses on practical strategies to assist with day-to-day tasks. They can recommend aids and modifications to minimise pain and improve function.

  4. Psychological Support:

    • Chronic pain often comes with emotional distress. Counselling, cognitive behavioural therapy (CBT), or mindfulness-based therapies can provide strategies to cope with pain, reduce stress, and improve mental well-being.

  5. Desensitisation Techniques:

    • Graded sensory retraining can help the nervous system ‘relearn’ normal responses to touch and pressure. This might include gentle brushing or tapping exercises under professional guidance.

  6. Neuromodulation:

    • In some resistant cases, devices like spinal cord stimulators or dorsal root ganglion stimulators may help interrupt pain pathways.

  7. Lifestyle Modifications:

    • Balanced diet, sufficient rest, low-impact aerobic exercise, and smoking cessation. These all support healing and potentially reduce inflammation.

The Importance of a Team Approach

CRPS is often best managed by a multidisciplinary team that may include:

  • Your GP or primary care doctor

  • Pain management specialists

  • Physiotherapists and occupational therapists

  • Psychologists or counsellors

  • Specialist surgeons (orthopaedic, plastic, or neurologic surgeons if required)

Collaboration ensures that all facets of the condition—physical, emotional, and social—are addressed comprehensively.

Final Thoughts

Chronic (Complex) Regional Pain Syndrome can be a debilitating condition, but with early recognition, evidence-based prevention, and effective multidisciplinary management, many patients can significantly improve their symptoms and quality of life. If you or someone you know is dealing with persistent, unexplained limb pain or has risk factors for CRPS after surgery or injury, don’t hesitate to seek prompt medical advice.

Disclaimer: This post is for informational purposes only and should not replace personalised medical advice. Always consult your healthcare professional for individualised treatment plans.

References & Further Reading

  • Harden RN, Oaklander AL, Burton AW, et al. Complex regional pain syndrome: practical diagnostic and treatment guidelines.

  • NIH – National Institute of Neurological Disorders and Stroke: Complex Regional Pain Syndrome Fact Sheet.

  • Australian Pain Society – Information about CRPS.

If you have any questions about CRPS or other chronic pain conditions, feel free to reach out. Remember: early intervention is key to preventing long-term complications. Stay informed, stay active, and prioritise your wellbeing.



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